Synthesis of starch-g-poly (acrylic acid-co-2-hydroxy ethyl methacrylate) as potential pH-sensitive hydrogelbased drug delivery system
نویسندگان
چکیده
منابع مشابه
Cisplatin delivery from poly(acrylic acid-co-methyl methacrylate) microparticles.
To develop a platform for tumor chemotherapy, poly(acrylic acid-co-methyl methacrylate) microparticles have been synthesized. Carboxylate containing monomers were included to complex therapeutic agents, specifically cisplatin. Microparticles were prepared by free radical emulsion polymerization in aqueous media. Particle diameter, zeta-potential, in vitro cytotoxicity, and in vivo acute toxicit...
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In this research, hydrogels based on poly vinyl alcohol and poly acrylic acid blend were prepared which were cross-linked by applied thermal conditions. Afterward, effects of time and heating on water uptake were investigated. The highest water uptake value exhibited by the sample that was heated for 20 min. at 110 ºC was about 2129% after 4 days at equilibrium state. Hydrogels exhibited p...
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Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...
متن کاملsynthesis of ph sensitive hydrogels based on poly vinyl alcohol and poly acrylic acid
in this research, hydrogels based on poly vinyl alcohol and poly acrylic acid blend were prepared which were cross-linked by applied thermal conditions. afterward, effects of time and heating on water uptake were investigated. the highest water uptake value exhibited by the sample that was heated for 20 min. at 110 ºc was about 2129% after 4 days at equilibrium state. hydrogels exhibited ph-sen...
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ژورنال
عنوان ژورنال: Indian Journal of Science and Technology
سال: 2011
ISSN: 0974-6846,0974-5645
DOI: 10.17485/ijst/2011/v4i9.11